treament for GBM

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treament for GBM

by BGreene on Tue Feb 27, 2018 12:00 AM

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We are researching the new paper that shows hydroxurea has worked in mice in conjunction with TMZ and radiation. We heard that there have been a doctor or two that has tried this in Germany or Europe.  Is there anyone that could put us in contact with this (or these ) doctors? Thank you for your prompt replies as time is of the essance in my husband's newely diagnosed GBM that has grown back 2 1/2 weeks after resect before we have even had time to implement a plan.

RE: treament for GBM

by jeanssister on Wed Feb 28, 2018 02:34 AM

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I found one paper, may've been the same one you read, and I copied over the medical facilities listed. I will also send a link to the article. The German facility mentioned is Franz-Hospital Dülmen, Dülmen, Germany. I also noticed Duke University was mentioned. They have a brain cancer center that I'd recommend contacting. Here's the link to the article, followed by the list I mentioned above: http://ascopubs.org/doi/full/10.1200/jco.2005.03.2185

From the Departments of Medicine, Pharmacology and Cancer Institute, University of Pittsburgh, Pittsburgh, PA; Franz-Hospital Dülmen, Dülmen, Germany; Novartis Pharmaceuticals, Florham Park, NJ; and Departments of Surgery, Neurology, Pediatrics, Radiology, Pathology, and Cancer Center Biostatistics, Duke University Medical Center, Durham, NC

I hope you find something!  Please keep us posted if you learn more.  Beth

RE: treament for GBM

by jeanssister on Wed Feb 28, 2018 02:39 AM

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This is a link to a list of clinical studies done in conjunction with glioblastoma and hydroxurea. Perhaps contacting one of these facilities will provide info for you:

https://clinicaltrials.gov/ct2/results?cond=Glioblastoma&

RE: treament for GBM

by BGreene on Wed Feb 28, 2018 06:58 AM

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Thank you so very much but the hydroxurea was combined with imatinib in this study so I don't think it was people who have tried hydroxurea and TMZ.  THANK YOU SO MUCH

I will share this with our doctor but it would have different results than combining TMZ with radiation and hydroxurea on newely diagnosed GMB.

I certainly will keep everyone posted as we continue our journey and search for drugs that will stop this dreaded disease.  THANK YOU FOR YOUR SUPPORT and if anyone hears of the doctor's in Germany or elsewhere that may be trying this PLEASE let us know.

RE: treament for GBM

by BGreene on Wed Feb 28, 2018 07:00 AM

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Thank you so very much but the hydroxurea was combined with other drugs in all of these studies so I don't think it was people who have tried hydroxurea and TMZ.  THANK YOU SO MUCH

I certainly will keep everyone posted as we continue our journey and search for drugs that will stop this dreaded disease.  THANK YOU FOR YOUR SUPPORT and if anyone hears of the doctor's in Germany or elsewhere that may be trying this PLEASE let us know.

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