Xofigo (radium 223) ?

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Xofigo (radium 223) ?

by OMB02 on Wed Jun 13, 2018 06:41 PM

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Is there anyone who is getting or has gotten Xofigo (radium 223) willing to share their experience with it ?

RE: Xofigo (radium 223) ?

by genemyers on Sun Jun 17, 2018 06:17 AM

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I have not had this treatment but from what I hear it is extremely well tolerated, given 6 infusions once a month for 6 months.  The treatment takes about 20 minutes to perform.  It only works on the bone.

They are currently doing clinical trials to see if patients can get a second round of 6 month treatments. 

In the clinical trial that approved this drug, some patients had a complete disappearance of cancer on their bone scans.

Best of Luck,

Gene

RE: Xofigo (radium 223) ?

by genemyers on Sun Jun 17, 2018 06:54 AM

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Most doctors time Radium so that you have a fair amount of bone mets before you get it.  The reason is that it only works on the bone mets and you currently can only get a round of Radium once, by 6 monthly injections.

Radium 223 has been in use for 6 years.

You can have Radium and then go on chemo, no problem as long as you are a candidate for chemo (called performance status).

An issue may occur due to a possible minimal myelosuppression (low blood cell counts) of the bone marrow from Radium, that if you were to go right onto chemo, the chemo might make it worse.  They might have to wait a little bit after Radium for you blood counts to normalize over time, which they normally do.

You can get drugs or a transfusion or wait for a while to reverse myelosuppression, but this is an issue that you should throughly discuss with your doctor so that you know what the plan is, if you are thinking of doing Radium and then Taxotere.

Best wishes,

Gene

RE: Xofigo (radium 223) ?

by OMB02 on Mon Jun 18, 2018 06:31 PM

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On Jun 17, 2018 6:54 AM genemyers wrote:

Most doctors time Radium so that you have a fair amount of bone mets before you get it.  The reason is that it only works on the bone mets and you currently can only get a round of Radium once, by 6 monthly injections.

Radium 223 has been in use for 6 years.

You can have Radium and then go on chemo, no problem as long as you are a candidate for chemo (called performance status).

An issue may occur due to a possible minimal myelosuppression (low blood cell counts) of the bone marrow from Radium, that if you were to go right onto chemo, the chemo might make it worse.  They might have to wait a little bit after Radium for you blood counts to normalize over time, which they normally do.

You can get drugs or a transfusion or wait for a while to reverse myelosuppression, but this is an issue that you should throughly discuss with your doctor so that you know what the plan is, if you are thinking of doing Radium and then Taxotere.

Best wishes,

Gene

Thank you Gene for the good info about radium 223. Greatly appreciated!

Take Care,

Monty

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