is it safe to have a baby while my husband is on keppra?

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is it safe to have a baby while my husband is on keppra?

by bl2860 on Sun Dec 29, 2019 05:23 AM

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Hi anyone know if it is safe to have a baby while taking keppra?

My husband was diagnosed with gbm 3/4 in April 2016, he had been taking temodar for over 2 years after surgery until July 2018, after that he is not taking any other meds except for keppra (400mg twice a day until now). we are now considering to have a second child, naturally, we know it won't be easy but we still wanted to give it a try. now the question is is it safe for me to conceive while my husband is on keppra? 

Any suggestions would be appreciated.

RE: is it safe to have a baby while my husband is on keppra?

by ToddlerFather on Mon Dec 30, 2019 02:35 AM

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On Dec 29, 2019 5:23 AM bl2860 wrote:

Hi anyone know if it is safe to have a baby while taking keppra?

My husband was diagnosed with gbm 3/4 in April 2016, he had been taking temodar for over 2 years after surgery until July 2018, after that he is not taking any other meds except for keppra (400mg twice a day until now). we are now considering to have a second child, naturally, we know it won't be easy but we still wanted to give it a try. now the question is is it safe for me to conceive while my husband is on keppra? 

Any suggestions would be appreciated.

If he was still taking temodar for the last 6-9 months that would be a risk, since temodar is teratogenic. Levetiracetam (Keppra) has no such known issues, but what is known is what you already mentioned, about sperm count and quality:

https://www.ncbi.nlm.nih.gov/pubmed/29889310

Since you might have to go to IVF to have a baby, I think the best route is to go to a fertility MD to discuss the situation and start doing the male-causes tests, including semen analysis of all factors (sperm count, motility, morphology, volume, color, fructose level, pH, liquefaction, viscosity, MOT, DNA damage, TMS, TMSC). That will measure whether your husband is affected or not, and how much. This, combined with your AMH test and age, will enable an informed decision on whether natural reproduction is feasible or not. 

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