Plus, there's no evidence of safety concerns linked to long-term use of the drug, researchers say
by Geneguy on Tue Dec 12, 2006 12:00 AM
by Np2000 on Sat Dec 16, 2006 12:00 AM
by Geneguy on Sat Dec 16, 2006 12:00 AM
On 12/16/2006 Np2000 wrote:I am totally horrified ready comments on this thread. My wife is going to have chemo with 5-FU in it. Should I contact the onc and ask him to allow her to check for DPD deficiency? or do you do the checking on your own?
by Np2000 on Sun Dec 17, 2006 12:00 AM
On 12/16/2006 Geneguy wrote: You can do it either way but I would suggest going through the onc doc and having him/her included in everything, especially for when the results come back so you can get a good interpretation. The test is covered by insurance and should be done on anyone prior to administration of 5-FU or any 5-FU cream. Somewhere around 3-5% of people will have an adverse reaction (toxicity) to 5-FU. This is high enough to not take a gamble on. Good luck to you and your wife.
I will contact the doctor's office first thing tomorrow. I am just surprised that they diddnt tell us anything about this during our "teaching" session.
by Np2000 on Mon Dec 18, 2006 12:00 AM
I called the nurse today and they have her scheduled for a test tomorrow. They did admit that this is a dangerous risk, but it is not standard testing.
thanks for the posting...
by Luckyj on Sun Jan 14, 2007 12:00 AM
by hamburger on Thu Aug 16, 2007 12:00 AM
My wife had a similar reaction to 5FU. She did survive but does have a slight memory deficit. We were told the same story re. the enzyme deficiency and that testing was not part of the standard of care
She spent 6 weeks in a Boston Hospital, one of those weeks was in the ICU. She suffered a pneumothorax due to a TPN line needed to feed her.
I was also told that we might loose her but luck was with us and we did'nt.
The cost of the test is minimal. Both your hosptalization and my wife's hospitalization costs were astronomical. Every one considering 5FU should be tested as part of the chemotherapy protocal.
I'm happy that things turfned out well for you.
by Snowmom60 on Thu Aug 16, 2007 12:00 AM
Now that you have all scared the you know what out of me, were any of you/loved one on continuous infusion 5FU? I'm on day 11, would I have already gotten the reaction?
by Geneguy on Thu Aug 16, 2007 12:00 AM
On 8/16/2007 hamburger wrote:Could you tell me how long this test has been available?
The test has been available since 1998.
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