TC and Increased Tumor Marker Levels after Surgery

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TC and Increased Tumor Marker Levels after Surgery

by swoody on Wed Dec 18, 2013 10:47 PM

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Hello all,

I was diagnosed with TC approximately 3 weeks ago - via blood tests and ultrasound. One week later I had a radical inguinal orchiectomy to remove the mass.

I just visisted my doctor yesterday (two weeks after surgery) and he took another blood sample for post-op tests. My cancer markers came back even higher than they were one week prior to surgery.

I had found a site online saying that " tumour marker levels may rise after effective treatment (possibly related to cell lysis), but the increase may not necessarily mean treatment failure. However, a consistent increase in tumour marker levels, coupled with lack of clinical improvement, may indicate treatment failure." ( )

I am hoping to find some more information regarding these markers, and if there are any situations where seeing a rise in them may not indicate the cancer has spread, or that it may be too soon after surgery for these markers to be reliable.

Is it likely that they could have increased between the time of my first blood test and my surgery? Thus appearing to be higher now, but which are actually lowering? How much time does it take for a noticable level of these markers to change? Are they nearly instantaneous, or does it take quite some time for the body to catch up and flush out old markers?

I was not nervous prior to the surgery, but the vagueness and possiblities that come with this latest blood test have me worried.

Thanks for any information you can provide!


RE: TC and Increased Tumor Marker Levels after Surgery

by swoody on Wed Dec 18, 2013 10:51 PM

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I should clarify, my doctor said it was stage I non-seminoma testicular cancer, if that makes any difference.

Thanks once again!

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