Clinical trial looking at THC-CBD used for Recurrent Glioblastoma

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Clinical trial looking at THC-CBD used for Recurrent Glioblastoma

by SmokeyNYY on Thu Nov 20, 2014 06:10 AM

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A Safety Study of Sativex in Combination With Dose-intense Temozolomide in Patients With Recurrent Glioblastoma

http://clinicaltrial.gov/ct2/show/NCT01812603?term=cannabidiol+cancer&rank=7

"This study follows several years of pre-clinical research conducted by GW in the field of glioma which has demonstrated that cannabinoids inhibit the viability of glioma cells both in vitro and in vivoi,ii via apoptosis or programmed cell death, may also affect angiogenesis, and have demonstrated tumor growth-inhibiting action and an improvement in the therapeutic efficacy of temozolomide1, a standard treatment for glioma. In addition, GW has shown tumor response to be positively associated with tissue levels of cannabinoids. GW has identified the putative mechanism of action for our cannabinoid product candidate, where autophagy and programmed cell death are stimulated via stimulation of the TRB3 pathway."

The main drug being used in this clinical trial should actually be approved to treat cancer pain in the USA in the next year or so cancer patients across the country can use it.

Some information you guys should be aware of.

RE: Clinical trial looking at THC-CBD used for Recurrent Glioblastoma

by SmokeyNYY on Thu Nov 20, 2014 06:21 AM

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RE: Clinical trial looking at THC-CBD used for Recurrent Glioblastoma

by Dodgerblue on Thu Nov 20, 2014 03:32 PM

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http://www.huffingtonpost.com/2014/11/18/marijuana-brain-can

Above is a mouse study and the jump to humans is a big one, but very interesting results.

Dodger

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