Study finds that most still recommend the breast cancer screen for women in their early 40s
by susel on Thu Dec 22, 2016 11:03 PM
My husband has been diagnosed with signet cell ring cancer of the appendix (SRCC-PMP)in september 2010:He had surgery (HIPEC_CRS) in november 2010. The percentage signet cell rings was not high then.October this year we found out that the cancer is back now. We are upset. My husband is 54 years old. The percentage signet ring cells is much higher now.There are mmetastases into the liver.Does anybody have experience with this extremely rare type of cancer ?It would be of great help to hear of anybody with the same type of cancer.thanksSusel
by gtgirlee on Mon Mar 13, 2017 12:28 PM
My husband was diagnosed with Stage III appendiceal mucinous cystadenocarcinoma with signet ring cell presence in July of 2015.
He underwent curative surgery to remove the 15cm tumor, substantial portions of the colon, and full cystectomy (removal of the bladder) as his tumor had pushed entirely through. He has a permanent urostomy at this point.
He underwent adjuvant chemo with the intent of preventing recurrence (FOLFOX). Just before completion of the 6 months a solitary pulmonary nodule was seen on a scan but it seemed incidental. 6 weeks later he had 7-- the doctors chalked it up to infection residuals (frequent infection due to lack of bladder and chemotherapy combined) because it did not light up on a PET scan. 6 months later and they doubled/tripled in diameter for those small nodules previously seen and several more ("innumberable" as per radiologist notes" seen in all lobes of the lungs. My husband at this point is on palliative chemotherapy in hopes to extend his life but it is taking its toll, and a recent infection required a chest Xray and we are fairly certain of additional growth which would indicate a seccond chemotherapy that did not prevent growth.
In December we were given 1-4 years depending on chemotherapy success by one doc and another recently said without chemo appx 6 months, and if it is effective we may gain 2-3 years.
Stage IV terminal diagnosis
K-RAS G12V mutation
Signet Ring Cell presence noted
MSS (Micro satellite stable)
Chemo treatments: FOLFOX, Ironetacan with Avastin
Surgery: Tumor removal, radical cystectomy, prostatectomy, removal of significant colon/intestine.
Small bowel obstruction surgery April 2016
Lung biopsy December 2016 (identified concurrent constrictive bronchiolitis)
When you track a discussion, you will get notified by e-mail if anyone else posts a new message on this discussion. Are you sure you want to track this discussion?
If you stop tracking this discussion, you will no longer get notified by e-mail if anyone else posts a new message on this discussion. Are you sure you want to stop tracking this discussion?
We care about your feedback. Let us know how we can improve your CancerCompass experience.