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Jcancom's Recent CancerCompass Activity

  • Jcancom has replied to a post on the message board

    critic, thank you for posting an update on this! It is very exciting to see that pharam is moving in on a variety of metabolic targets that all of us on the thread know so well. I am certainly thinking about all the implications that shutting off MCT-1 could have on the cancer environment. For example, as a guess I have wondering how exporting lactic acid and thus creating a negative surface charge on the cancer sur...

    Saturday at 5:43 PM view post
    • Jcancom has replied to a post on the message board

      critic, I'd love to hear your comments about the possibility that perhaps all the Bracht patients involved in the incident developed a TLS response. TLS can be fairly accurately characterized as when so many cancer cells are destroyed  so rapidly that the body cannot cope. Journal articles have been published in which even single cancer patients were reported that had TLS. TLS in solid tumors is thought to be v...

      June 17 at 6:09 PM view post
      • Jcancom has replied to a post on the message board

        Given what occurred at Bracht and the possible occurrence of multiple instances of TLS (in fact, perhaps most (all?) of the patients experienced TLS on the day of the main incident) a mature conversation might need to soon begin related to the choices that severely ill cancer patients should have access to. Under the spirit of Right to Try legislation would not cancer patients now have reasonable grounds to request ...

        June 16 at 1:31 AM view post
        • Jcancom has replied to a post on the message board

          The Bracht incident is becoming clarified. After a meticulous 2 year investigation it has been found that dosing of 3-BP was much much higher than would be considered typical. The reports talk of 3-6 times higher. That is a very large overdosing. I would have never felt comfortable going over the line with 3-BP: it stops glycolysis, therefore there are inherent dangers.This is part of the factual results from the inv...

          June 14 at 9:18 PM view post
          • Jcancom has replied to a post on the message board

            critic your last post has captured my interest. Did you notice who was behind this? I am wondering whether this might even be a 3-BP analogue. It is amazing the description they gave could very well be describing 3-BP. I would guess that there could be a wide range of modifications that you could make to the basic game plan and still arrive at a powerful cancer medicine. Perhaps they might want to tone down the bromi...

            June 12 at 12:29 AM view post
            • Jcancom has replied to a post on the message board

              critic there is so much optimistic news emerging in cancer research. A non-invasive method of treating brain tumors would be such a blessing. When cancer reaches the brain, it now seems almost untreatable; with the MRI scanner approach perhaps people with these mets could be treated possibly with continuing applications of these magnetic seeds. https://www.radiologybusiness.com/topics/care-delivery/researchers-deve...

              June 10 at 6:08 PM view post
              • Jcancom has replied to a post on the message board

                The investigation into Bracht appears to have made some progress. Does anyone have the details?

                June 09 at 3:11 AM view post
                • Jcancom has replied to a post on the message board

                  Startling result! Large study found that a large sub-group of breast cancer patients derive probably no benefit from chemotherapy.Those with a high score are known to benefit and those with a low score are known not to benefit much or at all. It was all those in the middle that they were not sure about. Latest result finds that those in the middle did not seem to benefit either. I have tried to be somewhat diploma...

                  June 05 at 11:46 PM view post
                  • Jcancom has replied to a post on the message board

                    critic, thank you for posting about the Right to Try Law! It is exciting that finally this is now the law of the land. Opening up innovation has to be a step in the right direction. I am constantly amazed at the overwhelming amount of research that is being published. Time and time again I have found new formulations that would very likely make existing treatments safer and more effective, though almost none of them...

                    June 04 at 12:29 AM view post
                    • Jcancom has replied to a post on the message board

                      Manuone I am glad that you found Daniel's blog! I was not sure what you had intended with the POH and 3-BP. There are several next generation 3-BP formulations that have been published lately, though it is still somewhat unclear how they gained cancer cell entry etc. .  Intranasal POH has a fair amount of encouraging clinical research as I am sure you are aware.   I am not certain whether intranasal 3-BP ...

                      May 16 at 3:12 AM view post
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